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Thyrotoxicosis from ectopic thyroid tissue

DOID EFO MESH SNOMED PheWeb

E4_THYTOXECT

Hyperthyroidism: Overactivity of the thyroid gland resulting in overproduction of thyroid hormone and increased metabolic rate. Causes include diffuse hyperplasia of the thyroid gland (Graves' disease), single nodule in the thyroid gland, and thyroiditis. The symptoms are related to the increased metabolic rate and include weight loss, fatigue, heat intolerance, excessive sweating, diarrhea, tachycardia, insomnia, muscle weakness, and tremor.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E05.3
Hospital discharge: ICD-9 2424
Cause of death: ICD-10 E05.3
Cause of death: ICD-9 2424

2 out of 7 registries used, show all original rules.

24

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Check minimum number of events None

24

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Include endpoints None

24

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Remove individuals based on genotype QC

23

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E4_THYTOXECT

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E05
Name in latin Thyreotoxicosis ex textu thyreoideo ectopico

Not enough data for upset plot.

Or the full data table

Summary Statistics

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Key figures

All Female Male
Number of individuals 23 22 -
Unadjusted prevalence (%) 0.01 0.01 -
Mean age at first event (years) 44.29 43.63 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_THYTOXECT – Thyrotoxicosis from ectopic thyroid tissue
GWS hits:

Survival analyses between endpoints

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Plot

before Thyrotoxicosis from ectopic thyroid tissue
after Thyrotoxicosis from ectopic thyroid tissue

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Drugs most likely to be purchased after Thyrotoxicosis from ectopic thyroid tissue

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Endpoint not on priority list, no data to show.