Autoimmune thyroiditis


autoimmune thyroid disease: Inflammatory disease of the thyroid gland due to autoimmune responses leading to lymphocytic infiltration of the gland. It is characterized by the presence of circulating thyroid antigen-specific T-cells and thyroid autoantibodies. The clinical signs can range from hypothyroidism to thyrotoxicosis depending on the type of autoimmune thyroiditis.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None


diagram downward connector

Check conditions None


diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E06.3
Hospital discharge: ICD-9 2452
Cause of death: ICD-10 E06.3
Cause of death: ICD-9 2452

2 out of 7 registries used, show all original rules.


diagram downward connector

Check minimum number of events None


diagram downward connector

Include endpoints None


diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC


diagram downward connector

Control definitions

Control exclude E4_THYROID

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E06
Name in latin Thyreoiditis autoimmunis

Summary Statistics

Key figures

All Female Male
Number of individuals 489 416 73
Unadjusted prevalence (%) 0.13 0.20 0.04
Mean age at first event (years) 42.26 41.55 46.30


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.97 [0.36, 2.58] 9.5e-1 19
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_THYROIDITAUTOIM – Autoimmune thyroiditis
GWS hits: 1

Survival analyses between endpoints


before Autoimmune thyroiditis
after Autoimmune thyroiditis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Autoimmune thyroiditis

Endpoint not on priority list, no data to show.