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Testicular hypofunction

DOID EFO MESH SNOMED PheWeb

E4_TESTICHYPO

testicular disease: A non-neoplastic or neoplastic disorder affecting the testis. Representative examples include torsion, infarction, germ cell tumor, sex cord-stromal tumor, lymphoma, and leukemia.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only males

172961

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Check conditions None

172961

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E29.1#
Hospital discharge: ICD-9 257[1-2]
Hospital discharge: ICD-8 2571
Cause of death: ICD-10 E29.1#
Cause of death: ICD-9 257[1-2]
Cause of death: ICD-8 2571
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 E29.1#

3 out of 7 registries used, show all original rules.

689

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Check minimum number of events None

689

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Include endpoints None

689

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Remove individuals based on genotype QC

667

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E4_TESTICHYPO

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E29
Name in latin Hypofunctio testium

Summary Statistics

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Key figures

All Female Male
Number of individuals 667 - 667
Unadjusted prevalence (%) 0.18 - 0.40
Mean age at first event (years) 50.39 - 50.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.15 9.62 [5.62, 16.47] 1.6e-16 28
15 years 0.04 4.92 [2.65, 9.14] 4.4e-7 14
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_TESTICHYPO – Testicular hypofunction
GWS hits:

Survival analyses between endpoints

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Plot

before Testicular hypofunction
after Testicular hypofunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Testicular hypofunction

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Endpoint not on priority list, no data to show.