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Hypothyroidism, strict autoimmune

PheWeb

E4_HYTHY_AI_STRICT

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not E4_HYTHY_AI_EXCL

381033

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

42333

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Remove individuals based on genotype QC

40926

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E4_HYTHY_AI_STRICT

Control definitions

Control exclude AUTOIMMUNE
Control conditions not E4_HYTHY_AI_EXCL

Extra metadata

First used in FinnGen datafreeze DF7

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 40926 32732 8194
Unadjusted prevalence (%) 10.85 15.53 4.93
Mean age at first event (years) 51.76 49.95 58.97

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.38 [1.18, 1.62] 7.1e-5 3175
15 years 0.01 1.03 [0.90, 1.18] 6.7e-1 1554
5 years 0.00 1.83 [1.62, 2.06] 2.6e-22 786
1 year 0.00 1.75 [1.43, 2.14] 6.5e-8 136

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_HYTHY_AI_STRICT – Hypothyroidism, strict autoimmune
GWS hits: 176

Survival analyses between endpoints

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Plot

before Hypothyroidism, strict autoimmune
after Hypothyroidism, strict autoimmune

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypothyroidism, strict autoimmune

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