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Other adrenocortical overactivity

DOID EFO MESH SNOMED PheWeb

E4_ADREACT

adrenal gland disease: A disease involving the adrenal gland.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E27.0
Hospital discharge: ICD-9 2553A
Hospital discharge: ICD-8 25508
Cause of death: ICD-10 E27.0
Cause of death: ICD-9 2553A
Cause of death: ICD-8 25508

2 out of 7 registries used, show all original rules.

153

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Check minimum number of events None

153

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Include endpoints None

153

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Remove individuals based on genotype QC

146

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E4_ADREACT

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E27
Name in latin Alia hyperfunctio adrenocorticalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 146 117 29
Unadjusted prevalence (%) 0.04 0.06 0.02
Mean age at first event (years) 24.14 19.84 41.50

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_ADREACT – Other adrenocortical overactivity
GWS hits:

Survival analyses between endpoints

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Plot

before Other adrenocortical overactivity
after Other adrenocortical overactivity

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other adrenocortical overactivity

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Endpoint not on priority list, no data to show.