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Other and unspecified coagulation defects

DOID EFO MESH SNOMED PheWeb

D3_COAGDEFNAS

blood coagulation disease: A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D68.8, D68.9
Hospital discharge: ICD-9 2869
Hospital discharge: ICD-8 2869
Cause of death: ICD-10 D68.8, D68.9
Cause of death: ICD-9 2869
Cause of death: ICD-8 2869

2 out of 7 registries used, show all original rules.

1258

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Check minimum number of events None

1258

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Include endpoints None

1258

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Remove individuals based on genotype QC

1217

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D3_COAGDEFNAS

Control definitions

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other and unspecified coagulation defects based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1217 864 353
Unadjusted prevalence (%) 0.32 0.41 0.21
Mean age at first event (years) 46.67 44.09 52.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.49 [1.62, 12.41] 3.8e-3 82
15 years 0.01 1.68 [0.56, 5.02] 3.6e-1 29
5 years 0.00 3.94 [1.45, 10.70] 7.2e-3 25
1 year 0.00 16.68 [6.98, 39.83] 2.4e-10 23

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: D3_COAGDEFNAS – Other and unspecified coagulation defects
GWS hits: 22

Survival analyses between endpoints

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Plot

before Other and unspecified coagulation defects
after Other and unspecified coagulation defects

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified coagulation defects

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Endpoint not on priority list, no data to show.