Other Crohn's disease

CHRONOTH

ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K50.8
Cause of death: ICD-10 K50.8

2 out of 7 registries used, show all original rules.

2166

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Check minimum number of events None

2166

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Include endpoints None

2166

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Remove individuals based on genotype QC

2098

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CHRONOTH

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Alis morbus Crohn specificatus

Summary Statistics

Key figures

All Female Male
Number of individuals 2098 1158 940
Unadjusted prevalence (%) 0.56 0.55 0.57
Mean age at first event (years) 42.49 41.72 43.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.50 [0.74, 3.02] 2.6e-1 68
15 years 0.01 1.12 [0.60, 2.08] 7.3e-1 32
5 years 0.00 2.50 [1.35, 4.66] 3.8e-3 19
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: CHRONOTH – Other Crohn's disease
GWS hits: 11

Survival analyses between endpoints

Plot

before Other Crohn's disease
after Other Crohn's disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other Crohn's disease

Endpoint not on priority list, no data to show.