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Other Crohn's disease

DOID EFO MESH PheWeb

CHRONOTH

ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K50.8
Cause of death: ICD-10 K50.8

2 out of 7 registries used, show all original rules.

2166

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Check minimum number of events None

2166

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Include endpoints None

2166

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Remove individuals based on genotype QC

2098

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CHRONOTH

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Alis morbus Crohn specificatus

Summary Statistics

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Key figures

All Female Male
Number of individuals 2098 1158 940
Unadjusted prevalence (%) 0.56 0.55 0.57
Mean age at first event (years) 42.49 41.72 43.45

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.50 [0.74, 3.02] 2.6e-1 68
15 years 0.01 1.12 [0.60, 2.08] 7.3e-1 32
5 years 0.00 2.50 [1.35, 4.66] 3.8e-3 19
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CHRONOTH – Other Crohn's disease
GWS hits: 11

Survival analyses between endpoints

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Plot

before Other Crohn's disease
after Other Crohn's disease

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other Crohn's disease

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Endpoint not on priority list, no data to show.