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Crohn's disease of large intestine

DOID EFO MESH PheWeb

CHRONLARGE

Crohn's colitis: Crohn's disease affecting the colon.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K50.1
Cause of death: ICD-10 K50.1

2 out of 7 registries used, show all original rules.

1633

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Check minimum number of events None

1633

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Include endpoints None

1633

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Remove individuals based on genotype QC

1581

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CHRONLARGE

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50
Name in latin Colitis regionalis

Summary Statistics

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Key figures

All Female Male
Number of individuals 1581 880 701
Unadjusted prevalence (%) 0.42 0.42 0.42
Mean age at first event (years) 43.03 41.82 44.55

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.00 [1.08, 3.70] 2.6e-2 68
15 years 0.01 1.28 [0.65, 2.51] 4.7e-1 33
5 years 0.00 1.87 [0.89, 3.92] 9.6e-2 15
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CHRONLARGE – Crohn's disease of large intestine
GWS hits: 5

Survival analyses between endpoints

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Plot

before Crohn's disease of large intestine
after Crohn's disease of large intestine

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Crohn's disease of large intestine

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Endpoint not on priority list, no data to show.