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Benign neoplasm: Rectum, anus and anal canal

DOID EFO MESH SNOMED PheWeb

CD2_BENIGN_RECTUM_ANAL

rectum cancer: A primary or metastatic malignant neoplasm that affects the rectum. Representative examples include carcinoma, lymphoma, and sarcoma.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

5782

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Remove individuals based on genotype QC

5613

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CD2_BENIGN_RECTUM_ANAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Benign neoplasm: Rectum, anus and anal canal based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 5613 2662 2951
Unadjusted prevalence (%) 1.49 1.26 1.77
Mean age at first event (years) 63.40 61.50 65.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.42 [1.01, 1.99] 4.3e-2 705
15 years 0.01 0.90 [0.69, 1.17] 4.3e-1 326
5 years 0.00 1.78 [1.43, 2.22] 2.6e-7 211
1 year 0.00 3.47 [2.62, 4.60] 3.7e-18 80

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_RECTUM_ANAL – Benign neoplasm: Rectum, anus and anal canal
GWS hits: 4

Survival analyses between endpoints

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Plot

before Benign neoplasm: Rectum, anus and anal canal
after Benign neoplasm: Rectum, anus and anal canal

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Drugs most likely to be purchased after Benign neoplasm: Rectum, anus and anal canal

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Endpoint not on priority list, no data to show.