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Benign neoplasm: Anus and anal canal

DOID EFO MESH SNOMED PheWeb

CD2_BENIGN_ANUS_ANAL_CANAL

anal neoplasm: A benign or malignant neoplasm that affects the anal canal or anal margin. Representative examples of benign neoplasms include squamous papilloma and papillary hidradenoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and melanoma.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D12.9&
Cause of death: ICD-10 D12.9&

2 out of 7 registries used, show all original rules.

754

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Check minimum number of events None

754

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Include endpoints None

754

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Remove individuals based on genotype QC

726

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CD2_BENIGN_ANUS_ANAL_CANAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 D12
Name in latin Neoplasma benignum ani

Similar endpoints

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List of similar endpoints to Benign neoplasm: Anus and anal canal based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 726 373 353
Unadjusted prevalence (%) 0.19 0.18 0.21
Mean age at first event (years) 62.02 59.38 64.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.03 [1.89, 4.85] 4.3e-6 118
15 years 0.01 1.67 [1.02, 2.71] 4.0e-2 61
5 years 0.00 2.08 [1.21, 3.58] 8.4e-3 34
1 year 0.00 4.27 [2.12, 8.60] 5.0e-5 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CD2_BENIGN_ANUS_ANAL_CANAL – Benign neoplasm: Anus and anal canal
GWS hits:

Survival analyses between endpoints

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Plot

before Benign neoplasm: Anus and anal canal
after Benign neoplasm: Anus and anal canal

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Drugs most likely to be purchased after Benign neoplasm: Anus and anal canal

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Endpoint not on priority list, no data to show.