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Autoimmune diseases excluding thyroid diseases, strict definition

PheWeb

AUTOIMMUNE_NONTHYROID_STRICT

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not (HYPOTHY_LEVOTHY
or GRAVES_COND
or E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM

341197

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

53630

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Remove individuals based on genotype QC

51863

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AUTOIMMUNE_NONTHYROID_STRICT

Control definitions

Control conditions not (HYPOTHY_LEVOTHY
or GRAVES_COND
or E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM

Extra metadata

First used in FinnGen datafreeze DF7

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 51863 27362 24501
Unadjusted prevalence (%) 13.75 12.98 14.74
Mean age at first event (years) 45.65 43.65 47.88

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.30 [2.05, 2.58] 5.5e-47 6166
15 years 0.01 1.56 [1.42, 1.72] 1.9e-20 2706
5 years 0.00 2.75 [2.52, 2.99] <1e-100 1541
1 year 0.00 5.71 [5.06, 6.44] <1e-100 645

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AUTOIMMUNE_NONTHYROID_STRICT – Autoimmune diseases excluding thyroid diseases, strict definition
GWS hits: 47

Survival analyses between endpoints

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Plot

before Autoimmune diseases excluding thyroid diseases, strict definition
after Autoimmune diseases excluding thyroid diseases, strict definition

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Autoimmune diseases excluding thyroid diseases, strict definition

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Endpoint not on priority list, no data to show.