Autoimmune diseases excluding thyroid diseases

AUTOIMMUNE_NONTHYROID

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector
diagram bullet

Check conditions

not (E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM
or E4_GRAVES_STRICT

347103

diagram downward connector

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

55015

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

53213

diagram downward connector
AUTOIMMUNE_NONTHYROID

Control definitions

Control conditions not (E4_HYTHY_AI_STRICT
or AUTOIMMUNE_HYPERTHYROIDISM
or E4_GRAVES_STRICT

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

Key figures

All Female Male
Number of individuals 53213 28407 24806
Unadjusted prevalence (%) 14.11 13.48 14.92
Mean age at first event (years) 45.70 43.80 47.88

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.07 [1.78, 2.40] 7.7e-22 6269
15 years 0.01 1.47 [1.30, 1.66] 1.6e-9 2747
5 years 0.00 2.68 [2.43, 2.95] 5.7e-88 1555
1 year 0.00 5.64 [4.98, 6.39] <1e-100 651

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AUTOIMMUNE_NONTHYROID – Autoimmune diseases excluding thyroid diseases
GWS hits: 53

Survival analyses between endpoints

Plot

before Autoimmune diseases excluding thyroid diseases
after Autoimmune diseases excluding thyroid diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Autoimmune diseases excluding thyroid diseases

Endpoint not on priority list, no data to show.