Asthma mixed form (mode) (more control exclusions)

ASTHMA_MIXED_EXMORE

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Check mode of ICD-10 codes: %J458

Hospital Discharge: ICD-10 J45.8

Cause of death: ICD-10 J45.8

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

1802

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ASTHMA_MIXED_EXMORE

Control definitions

Control exclude J10_ASTHMA, ALLERG_ASTHMA, VOCALCORDDYS, I9_HEARTFAIL, J10_HYPERSPNEUMONI, ASTHMA_EXCL

Extra metadata

First used in FinnGen datafreeze DF2

NAME	ASTHMA_MIXED_EXMORE
CONTROL_EXCLUDE	J10_ASTHMA\|ALLERG_ASTHMA\|VOCALCORDDYS\|I9_HEARTFAIL\|J10_HYPERSPNEUMONI\|ASTHMA_EXCL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	%J458
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	%J458
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Asthma mixed form (mode) (more control exclusions) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Asthma mixed form (mode)

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1802	1033	769
Unadjusted prevalence (%)	0.48	0.49	0.46
Mean age at first event (years)	49.30	44.89	55.22

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	3.88 [2.92, 5.15]	8.7e-21	326
15 years	0.01	2.02 [1.59, 2.56]	6.2e-9	142
5 years	0.00	3.11 [2.34, 4.14]	5.8e-15	98
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ASTHMA_MIXED_EXMORE – Asthma mixed form (mode) (more control exclusions)
GWS hits:

Survival analyses between endpoints

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Plot

before Asthma mixed form (mode) (more control exclusions)
after Asthma mixed form (mode) (more control exclusions)

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Table

Loading survival analyses table

Drugs most likely to be purchased after Asthma mixed form (mode) (more control exclusions)

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Endpoint not on priority list, no data to show.