Childhood asthma (age<16) (more control exclusions)

ASTHMA_CHILD_EXMORE

No definition available.

Endpoint definition

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FinnGen phenotype data

individuals

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Apply sex-specific rule None

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Check conditions None

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Check pre-conditions, main-only, mode, registry filters

Pre-conditions EVENT_AGE<16

Hospital Discharge: ICD-10 J45, J46

Hospital discharge: ICD-9 493

Hospital discharge: ICD-8 493

Cause of death: ICD-10 J45, J46

Cause of death: ICD-9 493

Cause of death: ICD-8 493

2 out of 7 registries used, show all original rules.

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Check minimum number of events None

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Include endpoints None

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Remove individuals based on genotype QC

5865

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ASTHMA_CHILD_EXMORE

Control definitions

Control exclude J10_ASTHMA, ALLERG_ASTHMA, VOCALCORDDYS, I9_HEARTFAIL, J10_HYPERSPNEUMONI, ASTHMA_EXCL

Extra metadata

First used in FinnGen datafreeze DF2

NAME	ASTHMA_CHILD_EXMORE
CONTROL_EXCLUDE	J10_ASTHMA\|ALLERG_ASTHMA\|VOCALCORDDYS\|I9_HEARTFAIL\|J10_HYPERSPNEUMONI\|ASTHMA_EXCL
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS	EVENT_AGE<16
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J45\|J46
HD_ICD_9	493
HD_ICD_8	493
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J45\|J46
COD_ICD_9	493
COD_ICD_8	493
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Childhood asthma (age<16) (more control exclusions) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Childhood asthma (age<16)

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	5865	3453	2412
Unadjusted prevalence (%)	1.56	1.64	1.45
Mean age at first event (years)	7.44	7.94	6.71

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.65 [2.26, 5.90]	1.3e-7	31
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ASTHMA_CHILD_EXMORE – Childhood asthma (age<16) (more control exclusions)
GWS hits: 14

Survival analyses between endpoints

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Plot

before Childhood asthma (age<16) (more control exclusions)
after Childhood asthma (age<16) (more control exclusions)

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Childhood asthma (age<16) (more control exclusions)

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Endpoint not on priority list, no data to show.