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Asthma and allergy

DOID EFO MESH SNOMED PheWeb

ASTHMA_ALLERG

allergic rhinitis: Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes of the sinuses, eyes, middle ear, and pharynx. Symptoms include sneezing, nasal congestion, rhinorrhea, and itching. It may lead to fatigue, drowsiness, and malaise thus causing impairment of the quality of life.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

ALLERG_ASTHMA

9996

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

4821

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Remove individuals based on genotype QC

4647

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ASTHMA_ALLERG

Control definitions

Control conditions not ALLERG_ASTHMA

Extra metadata

First used in FinnGen datafreeze DF2

No data for upset plot.

No data for upset table.

Summary Statistics

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Key figures

All Female Male
Number of individuals 4647 3337 1310
Unadjusted prevalence (%) 1.23 1.58 0.79
Mean age at first event (years) 27.29 28.01 25.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.16 [0.72, 1.89] 5.4e-1 79
15 years 0.01 1.07 [0.65, 1.75] 7.9e-1 37
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ASTHMA_ALLERG – Asthma and allergy
GWS hits: 12

Survival analyses between endpoints

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Plot

before Asthma and allergy
after Asthma and allergy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Asthma and allergy

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Endpoint not on priority list, no data to show.