Asthma-related acute respiratory infections

DOID EFO MESH SNOMED PheWeb

ASTHMA_ACUTE_RESPIRATORY_INFECTIONS

bronchitis: An acute or chronic inflammatory process affecting the bronchi. [database_cross_reference: NCIT:C2911]

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions

J10_ASTHMA

43630

Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

Check minimum number of events None

Include endpoints

J10_SINUSITIS

J10_PHARYNGITIS

J10_TONSILLITIS

BRONCHITIS

16592

Remove individuals based on genotype QC

16018

ASTHMA_ACUTE_RESPIRATORY_INFECTIONS

Control definitions

Control exclude ASTHMA_INFECTIONS

Control conditions not J10_ASTHMA

Extra metadata

First used in FinnGen datafreeze DF2

NAME	ASTHMA_ACUTE_RESPIRATORY_INFECTIONS
CONTROL_EXCLUDE	ASTHMA_INFECTIONS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS	!J10_ASTHMA
SEX
INCLUDE	J10_SINUSITIS\|J10_PHARYNGITIS\|J10_TONSILLITIS\|BRONCHITIS
PRE_CONDITIONS
CONDITIONS	J10_ASTHMA
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

No data for upset plot.

No data for upset table.

Similar endpoints

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List of similar endpoints to Asthma-related acute respiratory infections based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	16018	9513	6505
Unadjusted prevalence (%)	4.25	4.51	3.91
Mean age at first event (years)	40.40	41.24	39.17

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	2.98 [2.44, 3.65]	1.9e-26	1718
15 years	0.01	1.62 [1.38, 1.92]	8.3e-9	678
5 years	0.00	3.20 [2.76, 3.72]	2.5e-52	512
1 year	0.00	8.12 [6.79, 9.69]	<1e-100	259

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ASTHMA_ACUTE_RESPIRATORY_INFECTIONS – Asthma-related acute respiratory infections
GWS hits: 16

Survival analyses between endpoints

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Plot

before Asthma-related acute respiratory infections
after Asthma-related acute respiratory infections

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Asthma-related acute respiratory infections

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3