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Acute appendicitis, with complications

DOID EFO MESH SNOMED PheWeb

APPENDACUT_COMPLIC

appendicitis: Acute inflammation of the vermiform appendix.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K35.0, K35.1
Hospital discharge: ICD-9 540[0-1]
Hospital discharge: ICD-8 540
Hospital discharge: excluded ICD-8 54090|54099
Cause of death: ICD-10 K35.0, K35.1
Cause of death: ICD-9 540[0-1]
Cause of death: ICD-8 540
Cause of death: excluded ICD-8 54090|54099

2 out of 7 registries used, show all original rules.

6927

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Check minimum number of events None

6927

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Include endpoints None

6927

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Remove individuals based on genotype QC

6747

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APPENDACUT_COMPLIC

Control definitions

Control exclude K11_APPENDIX

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 6747 3212 3535
Unadjusted prevalence (%) 1.79 1.52 2.13
Mean age at first event (years) 36.63 34.47 38.59

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.92 [0.68, 1.24] 5.7e-1 717
15 years 0.00 0.76 [0.59, 0.97] 3.0e-2 317
5 years 0.00 1.10 [0.86, 1.42] 4.4e-1 116
1 year 0.00 2.38 [1.69, 3.34] 5.7e-7 46

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: APPENDACUT_COMPLIC – Acute appendicitis, with complications
GWS hits: 4

Survival analyses between endpoints

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Plot

before Acute appendicitis, with complications
after Acute appendicitis, with complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute appendicitis, with complications

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Endpoint not on priority list, no data to show.