Intestinal infectious diseases

AB1_INTESTINAL_INFECTIONS

amebiasis: A parasitic protozoa infectious disease that involves infection caused by the amoeba Entamoeba histolytica. Amebic invasion of the intestinal lining causes dysentery, colitis or diarrhea. The infection can also spread through the blood to the liver and, rarely, to the lungs, brain or other organs.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 A00-A09
Hospital discharge: ICD-9 00[1-9]
Hospital discharge: ICD-8 00[0-9]
Cause of death: ICD-10 A00-A09
Cause of death: ICD-9 00[1-9]
Cause of death: ICD-8 00[0-9]

2 out of 7 registries used, show all original rules.

42473

diagram downward connector

Check minimum number of events None

42473

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

40881

diagram downward connector
AB1_INTESTINAL_INFECTIONS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Intestinal infectious diseases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 40881 22337 18544
Unadjusted prevalence (%) 10.84 10.60 11.15
Mean age at first event (years) 40.55 39.31 42.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.26 [2.78, 3.82] 2.2e-48 5471
15 years 0.01 1.56 [1.38, 1.77] 1.7e-12 1717
5 years 0.00 4.02 [3.63, 4.44] <1e-100 1817
1 year 0.00 12.45 [11.05, 14.03] <1e-100 1305

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: AB1_INTESTINAL_INFECTIONS – Intestinal infectious diseases
GWS hits: 1

Survival analyses between endpoints

Plot

before Intestinal infectious diseases
after Intestinal infectious diseases

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Intestinal infectious diseases

Endpoint not on priority list, no data to show.