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Intestinal infectious diseases

DOID EFO MESH PheWeb

AB1_INTESTINAL_INFECTIONS

amebiasis: A parasitic protozoa infectious disease that involves infection caused by the amoeba Entamoeba histolytica. Amebic invasion of the intestinal lining causes dysentery, colitis or diarrhea. The infection can also spread through the blood to the liver and, rarely, to the lungs, brain or other organs.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 A00-A09
Hospital discharge: ICD-9 00[1-9]
Hospital discharge: ICD-8 00[0-9]
Cause of death: ICD-10 A00-A09
Cause of death: ICD-9 00[1-9]
Cause of death: ICD-8 00[0-9]

2 out of 7 registries used, show all original rules.

42473

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Check minimum number of events None

42473

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Include endpoints

42473

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Remove individuals based on genotype QC

40881

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AB1_INTESTINAL_INFECTIONS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Intestinal infectious diseases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 40881 22337 18544
Unadjusted prevalence (%) 10.84 10.60 11.15
Mean age at first event (years) 40.55 39.31 42.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.26 [2.78, 3.82] 2.2e-48 5471
15 years 0.01 1.56 [1.38, 1.77] 1.7e-12 1717
5 years 0.00 4.02 [3.63, 4.44] <1e-100 1817
1 year 0.00 12.45 [11.05, 14.03] <1e-100 1305

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: AB1_INTESTINAL_INFECTIONS – Intestinal infectious diseases
GWS hits: 1

Survival analyses between endpoints

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Plot

before Intestinal infectious diseases
after Intestinal infectious diseases

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Drugs most likely to be purchased after Intestinal infectious diseases

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Endpoint not on priority list, no data to show.