Vitamin deficiency


ascorbic acid deficiency: A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into scurvy in young children fed unsupplemented cow's milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Control exclude E4_NUTRIDEF

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1334 763 571
Unadjusted prevalence (%) 0.35 0.36 0.34
Mean age at first event (years) 54.14 50.43 59.10


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.44 [1.35, 4.43] 3.3e-3 254
15 years 0.01 1.21 [0.64, 2.28] 5.6e-1 107
5 years 0.00 2.96 [1.81, 4.82] 1.4e-5 93
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: VIT_DEF – Vitamin deficiency
GWS hits:

Survival analyses between endpoints


before Vitamin deficiency
after Vitamin deficiency

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Drugs most likely to be purchased after Vitamin deficiency

Endpoint not on priority list, no data to show.