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Respiratory tuberculosis

DOID EFO MESH SNOMED PheWeb

TBC_RESP

pulmonary tuberculosis: A bacterial infection that affects the lungs and is caused by Mycobacterium tuberculosis. Most patients with tuberculosis do not have symptoms (latent tuberculosis) and are not contagious. When signs and symptoms occur (active tuberculosis), patients become contagious. The signs and symptoms include chronic cough with blood-tinged sputum, night sweats, fever, fatigue, and weight loss.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

1870

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Remove individuals based on genotype QC

1793

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TBC_RESP

Control definitions

Control exclude IBD_TUBERCULOSIS

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Respiratory tuberculosis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 1793 592 1201
Unadjusted prevalence (%) 0.48 0.28 0.72
Mean age at first event (years) 47.69 40.20 51.38

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.95 [2.40, 3.63] 6.8e-25 675
15 years 0.01 1.71 [1.47, 2.00] 1.5e-11 290
5 years 0.00 2.75 [2.31, 3.27] 3.0e-30 161
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: TBC_RESP – Respiratory tuberculosis
GWS hits:

Survival analyses between endpoints

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Plot

before Respiratory tuberculosis
after Respiratory tuberculosis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Respiratory tuberculosis

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Endpoint not on priority list, no data to show.