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Fracture of lower leg, including ankle

MESH PheWeb

ST19_FRACT_LOWER_LEG_INCLU_ANKLE

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 S82
Cause of death: ICD-10 S82

2 out of 7 registries used, show all original rules.

20629

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Check minimum number of events None

20629

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Include endpoints None

20629

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Remove individuals based on genotype QC

19994

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ST19_FRACT_LOWER_LEG_INCLU_ANKLE

Control definitions

Control exclude ST19_INJURI_KNEE_LOWER_LEG

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 S8
Name in latin Fractura genus/cruris

Summary Statistics

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Key figures

All Female Male
Number of individuals 19994 11552 8442
Unadjusted prevalence (%) 5.30 5.48 5.08
Mean age at first event (years) 50.90 51.78 49.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.22 [1.86, 2.64] 9.5e-19 1725
15 years 0.01 1.40 [1.19, 1.65] 5.8e-5 791
5 years 0.00 2.77 [2.40, 3.20] 7.4e-44 488
1 year 0.00 4.45 [3.64, 5.44] 2.7e-48 153

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: ST19_FRACT_LOWER_LEG_INCLU_ANKLE – Fracture of lower leg, including ankle
GWS hits: 5

Survival analyses between endpoints

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Plot

before Fracture of lower leg, including ankle
after Fracture of lower leg, including ankle

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Fracture of lower leg, including ankle

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Endpoint not on priority list, no data to show.