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Spondyloarthritis

PheWeb

SPONDYLOARTHRITIS

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M45, M45+H22.1, M45+J99.8, M46
Hospital discharge: ICD-9 720
Hospital discharge: ICD-8 7124|7131|72699
Cause of death: ICD-10 M45, M45+H22.1, M45+J99.8, M46
Cause of death: ICD-9 720
Cause of death: ICD-8 7124|7131|72699

2 out of 7 registries used, show all original rules.

6540

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Check minimum number of events None

6540

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Include endpoints None

6540

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Remove individuals based on genotype QC

6333

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SPONDYLOARTHRITIS

Control definitions

Control exclude ILD_SYST_AUTO_DISEASES

Extra metadata

First used in FinnGen datafreeze DF2

Similar endpoints

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Summary Statistics

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Key figures

All Female Male
Number of individuals 6333 3173 3160
Unadjusted prevalence (%) 1.68 1.51 1.90
Mean age at first event (years) 45.68 43.98 47.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.69 [1.29, 2.21] 1.3e-4 902
15 years 0.01 1.13 [0.94, 1.36] 1.8e-1 423
5 years 0.00 1.59 [1.32, 1.90] 6.3e-7 185
1 year 0.00 3.09 [2.36, 4.06] 3.6e-16 68

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: SPONDYLOARTHRITIS – Spondyloarthritis
GWS hits: 10

Survival analyses between endpoints

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Plot

before Spondyloarthritis
after Spondyloarthritis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Spondyloarthritis

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Endpoint not on priority list, no data to show.