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Small fibre neuropathy

DOID MESH PheWeb

SFN

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G60.8, G62.8, G63.3*
Cause of death: ICD-10 G60.8, G62.8, G63.3*

2 out of 7 registries used, show all original rules.

621

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Check minimum number of events None

621

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Include endpoints None

621

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Remove individuals based on genotype QC

600

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SFN

Control definitions

Control exclude G6_POLYNEU

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 600 255 345
Unadjusted prevalence (%) 0.16 0.12 0.21
Mean age at first event (years) 62.07 59.13 64.24

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.62 [1.47, 8.89] 5.1e-3 73
15 years 0.01 1.39 [0.50, 3.83] 5.2e-1 25
5 years 0.00 3.40 [1.48, 7.78] 3.8e-3 29
1 year 0.00 9.07 [4.14, 19.85] 3.4e-8 16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: SFN – Small fibre neuropathy
GWS hits:

Survival analyses between endpoints

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Plot

before Small fibre neuropathy
after Small fibre neuropathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Small fibre neuropathy

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Endpoint not on priority list, no data to show.