Statin medication

RX_STATIN

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC C10AA

1 out of 7 registries used, show all original rules.

131287

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Check minimum number of events

Min. number of events 3

131287

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Include endpoints None

131287

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Remove individuals based on genotype QC

127169

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RX_STATIN

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF4

Summary Statistics

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Key figures

All Female Male
Number of individuals 127169 58014 69155
Unadjusted prevalence (%) 33.72 27.52 41.59
Mean age at first event (years) 59.53 59.68 59.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.30 [1.21, 1.40] 1.5e-12 16967
15 years 0.01 1.08 [1.02, 1.16] 1.6e-2 9877
5 years 0.00 1.32 [1.24, 1.40] 1.0e-17 3112
1 year 0.00 0.89 [0.78, 1.02] 9.6e-2 356

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_STATIN – Statin medication
GWS hits: 186

Survival analyses between endpoints

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Plot

before Statin medication
after Statin medication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Statin medication

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