Biological medication for rheuma

RX_RHEUMA_BIOLOGICAL

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC L04AA24|L04AC03|L04AB04|L04AB01|L04AB06|L04AB02|L04AB05|L04AA26|L01XC02|L04AC10|L04AC07|L04AC05

1 out of 7 registries used, show all original rules.

4367

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Check minimum number of events

Min. number of events 3

4367

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Include endpoints None

4367

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Remove individuals based on genotype QC

4235

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RX_RHEUMA_BIOLOGICAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

NAME	RX_RHEUMA_BIOLOGICAL
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC	L04AA24\|L04AC03\|L04AB04\|L04AB01\|L04AB06\|L04AB02\|L04AB05\|L04AA26\|L01XC02\|L04AC10\|L04AC07\|L04AC05
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Biological medication for rheuma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4235	2607	1628
Unadjusted prevalence (%)	1.12	1.24	0.98
Mean age at first event (years)	46.92	46.75	47.18

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	3.55 [2.00, 6.30]	1.6e-5	64
15 years	0.02	2.44 [1.34, 4.43]	3.4e-3	44
5 years	0.00	1.93 [0.98, 3.80]	5.6e-2	13
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_RHEUMA_BIOLOGICAL – Biological medication for rheuma
GWS hits: 4

Survival analyses between endpoints

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Plot

before Biological medication for rheuma
after Biological medication for rheuma

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Biological medication for rheuma

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Endpoint not on priority list, no data to show.