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Use of hypnotics and sedatives

PheWeb

RX_N05C

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC N05C

1 out of 7 registries used, show all original rules.

68070

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Check minimum number of events

Min. number of events 3

68070

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Include endpoints None

68070

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Remove individuals based on genotype QC

65814

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RX_N05C

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 65814 38744 27070
Unadjusted prevalence (%) 17.45 18.38 16.28
Mean age at first event (years) 52.06 50.13 54.81

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.76 [1.60, 1.93] 1.5e-32 11610
15 years 0.01 1.34 [1.23, 1.45] 6.6e-13 5734
5 years 0.00 1.97 [1.84, 2.12] 3.1e-74 2626
1 year 0.00 2.04 [1.80, 2.31] 9.6e-29 520

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_N05C – Use of hypnotics and sedatives
GWS hits: 20

Survival analyses between endpoints

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Plot

before Use of hypnotics and sedatives
after Use of hypnotics and sedatives

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Use of hypnotics and sedatives

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Endpoint not on priority list, no data to show.