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Codeine or tramadol medication

PheWeb

RX_CODEINE_TRAMADOL

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Medicine purchases: ATC N02A02|N02AJ0|N02AJ1[3-5]|N02AA59|N02AA79

1 out of 7 registries used, show all original rules.

59633

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Check minimum number of events

Min. number of events 3

59633

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Include endpoints None

59633

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Remove individuals based on genotype QC

57823

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RX_CODEINE_TRAMADOL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF5

Summary Statistics

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Key figures

All Female Male
Number of individuals 57823 33732 24091
Unadjusted prevalence (%) 15.33 16.00 14.49
Mean age at first event (years) 54.30 52.36 57.02

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.85 [2.46, 3.29] 1.5e-44 3846
15 years 0.01 1.68 [1.47, 1.91] 5.4e-15 2153
5 years 0.00 2.90 [2.59, 3.23] 7.5e-80 1408
1 year 0.00 3.14 [2.68, 3.68] 7.5e-45 276

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RX_CODEINE_TRAMADOL – Codeine or tramadol medication
GWS hits: 8

Survival analyses between endpoints

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Plot

before Codeine or tramadol medication
after Codeine or tramadol medication

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Codeine or tramadol medication

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Endpoint not on priority list, no data to show.