Other/unspecified rheumatoid arthritis

RHEUMA_NOS

rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M06.8, M06.9

Hospital discharge: ICD-9 7148

Hospital discharge: ICD-8 7123[8-9]

Cause of death: ICD-10 M06.8, M06.9

Cause of death: ICD-9 7148

Cause of death: ICD-8 7123[8-9]

2 out of 7 registries used, show all original rules.

3968

Check minimum number of events None

3968

Include endpoints None

3968

Remove individuals based on genotype QC

3876

RHEUMA_NOS

Control definitions

Control exclude STILL_ADULT

Extra metadata

First used in FinnGen datafreeze DF2

NAME	RHEUMA_NOS
CONTROL_EXCLUDE	STILL_ADULT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M06[8-9]
HD_ICD_9	7148
HD_ICD_8	7123[8-9]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M06[8-9]
COD_ICD_9	7148
COD_ICD_8	7123[8-9]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Other/unspecified rheumatoid arthritis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

3876

2608

1268

Unadjusted prevalence (%)

1.03

1.24

0.76

Mean age at first event (years)

50.07

48.20

53.91

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.15 [2.52, 3.94]	9.0e-24	732
15 years	0.01	1.73 [1.41, 2.12]	1.3e-7	291
5 years	0.00	3.33 [2.67, 4.14]	4.7e-27	195
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RHEUMA_NOS – Other/unspecified rheumatoid arthritis
GWS hits: 4

Survival analyses between endpoints

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Plot

before Other/unspecified rheumatoid arthritis
after Other/unspecified rheumatoid arthritis

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Table

Loading survival analyses table

Drugs most likely to be purchased after Other/unspecified rheumatoid arthritis

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3

Other/unspecified rheumatoid arthritis

Endpoint definition

All original rules

Upset plot

Case counts by code for Other/unspecified rheumatoid arthritis (RHEUMA_NOS)

Similar endpoints

Summary Statistics

Key figures

Number of individuals

Unadjusted prevalence

Mean age at first event

Follow-up

Absolute risk

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Number of individuals (N)

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Authentication required

Survival analyses between endpoints

Plot

Table

Drugs most likely to be purchased after Other/unspecified rheumatoid arthritis