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Reactive arthropathies, FINNGEN

DOID EFO MESH SNOMED PheWeb

RHEUMA_ARHTROPAT_REACTIVE

reactive arthritis: Reactive arthritis (ReA) is an autoimmune disorder belonging to the group of seronegative spondyloarthropathies and is characterized by the classic triad of arthritis, urethritis and conjunctivitis.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters None

0 out of 7 registries used, show all original rules.

0

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Check minimum number of events None

0

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Include endpoints

2219

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Remove individuals based on genotype QC

2158

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RHEUMA_ARHTROPAT_REACTIVE

Control definitions

Control exclude RHEUMA_ENDPOINTS

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 2158 1223 935
Unadjusted prevalence (%) 0.57 0.58 0.56
Mean age at first event (years) 46.60 44.24 49.69

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.50 [1.63, 3.84] 2.9e-5 129
15 years 0.01 1.61 [1.06, 2.45] 2.5e-2 59
5 years 0.00 3.26 [2.15, 4.93] 2.4e-8 35
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: RHEUMA_ARHTROPAT_REACTIVE – Reactive arthropathies, FINNGEN
GWS hits: 1

Survival analyses between endpoints

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Plot

before Reactive arthropathies, FINNGEN
after Reactive arthropathies, FINNGEN

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Reactive arthropathies, FINNGEN

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Endpoint not on priority list, no data to show.