Other congenital malformations

DOID MESH PheWeb

Q17_OTHER_CONGEN_MALFO

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 Q80-Q89

Cause of death: ICD-10 Q80-Q89

2 out of 7 registries used, show all original rules.

2665

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Check minimum number of events None

2665

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Include endpoints

Q17_CONGEN_ICHTHYOSIS

Q17_EPIDERMOL_BULLOSA

Q17_OTHER_CONGEN_MALFO_SKIN

Q17_CONGEN_MALFO_BREAST

Q17_OTHER_CONGEN_MALFO_INTEG

Q17_PHAKOMATOSES_NOT_ELSEW_CLASSIFIED

Q17_CONGEN_MALFO_SYNDR_KNOWN_EXOGE_CAUSES_NOT_ELSEW_CLASSIFIED

Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS

Q17_OTHER_CONGEN_MALFO_NOT_ELSEW_CLASSIFIED

2665

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Remove individuals based on genotype QC

2550

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Q17_OTHER_CONGEN_MALFO

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF4

Parent code in ICD-10 Q

Name in latin Aliae malformationes congenitae

NAME	Q17_OTHER_CONGEN_MALFO
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	Q17_CONGEN_ICHTHYOSIS\|Q17_EPIDERMOL_BULLOSA\|Q17_OTHER_CONGEN_MALFO_SKIN\|Q17_CONGEN_MALFO_BREAST\|Q17_OTHER_CONGEN_MALFO_INTEG\|Q17_PHAKOMATOSES_NOT_ELSEW_CLASSIFIED\|Q17_CONGEN_MALFO_SYNDR_KNOWN_EXOGE_CAUSES_NOT_ELSEW_CLASSIFIED\|Q17_OTHER_SPECIFE_CONGEN_MALFO_SYNDR_AFFECTING_MULTIPLE_SYSTEMS\|Q17_OTHER_CONGEN_MALFO_NOT_ELSEW_CLASSIFIED
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q8
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q8
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Other congenital malformations based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2550	1736	814
Unadjusted prevalence (%)	0.68	0.82	0.49
Mean age at first event (years)	36.20	35.65	37.36

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	2.65 [1.71, 4.12]	1.5e-5	110
15 years	0.01	1.59 [1.00, 2.53]	4.9e-2	54
5 years	0.00	2.03 [1.19, 3.47]	9.4e-3	21
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_OTHER_CONGEN_MALFO – Other congenital malformations
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other congenital malformations
after Other congenital malformations

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Table

Loading survival analyses table

Drugs most likely to be purchased after Other congenital malformations

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Endpoint not on priority list, no data to show.