Congenital deformities of hip

PheWeb

Q17_LVOTO_BROAD

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 Q24.4, Q25.1, Q25.20, Q25.3, Q25.40

Hospital discharge: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B

Hospital discharge: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875

Hospital discharge: excluded ICD-9 758|7595|75683

Cause of death: ICD-10 Q24.4, Q25.1, Q25.20, Q25.3, Q25.40

Cause of death: ICD-9 7463A|7464A|7463D|7465A|7466A|7467A|7468X|7463X|7471A|7472B|7471B

Cause of death: excluded ICD-10 Q90|Q91|Q92|Q93|Q96|Q8780|Q8781|Q8782|Q8783|Q8784|Q8786|Q8788|Q85|Q796|Q874|Q875

Cause of death: excluded ICD-9 758|7595|75683

2 out of 7 registries used, show all original rules.

385

Check minimum number of events None

385

Include endpoints

I9_AORTVALV_EARLY

2988

Remove individuals based on genotype QC

2891

Q17_LVOTO_BROAD

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF7

NAME	Q17_LVOTO_BROAD
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	I9_AORTVALV_EARLY
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q244\|Q251\|Q2520\|Q253\|Q2540
HD_ICD_9	7463A\|7464A\|7463D\|7465A\|7466A\|7467A\|7468X\|7463X\|7471A\|7472B\|7471B
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL	Q90\|Q91\|Q92\|Q93\|Q96\|Q8780\|Q8781\|Q8782\|Q8783\|Q8784\|Q8786\|Q8788\|Q85\|Q796\|Q874\|Q875
HD_ICD_9_EXCL	758\|7595\|75683
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q244\|Q251\|Q2520\|Q253\|Q2540
COD_ICD_9	7463A\|7464A\|7463D\|7465A\|7466A\|7467A\|7468X\|7463X\|7471A\|7472B\|7471B
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL	Q90\|Q91\|Q92\|Q93\|Q96\|Q8780\|Q8781\|Q8782\|Q8783\|Q8784\|Q8786\|Q8788\|Q85\|Q796\|Q874\|Q875
COD_ICD_9_EXCL	758\|7595\|75683
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Congenital deformities of hip based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Aortic valve malfunction, age under 60 years

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2891	1061	1830
Unadjusted prevalence (%)	0.77	0.50	1.10
Mean age at first event (years)	46.39	44.89	47.26

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.36 [1.35, 4.13]	2.6e-3	197
15 years	0.01	1.94 [1.22, 3.08]	4.8e-3	95
5 years	0.00	3.34 [2.05, 5.46]	1.4e-6	35
1 year	0.00	8.99 [4.90, 16.48]	1.2e-12	16

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: Q17_LVOTO_BROAD – Congenital deformities of hip
GWS hits: 1

Survival analyses between endpoints

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Plot

before Congenital deformities of hip
after Congenital deformities of hip

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Table

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Drugs most likely to be purchased after Congenital deformities of hip

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3