≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Craniosynostosis EXCLUDE syndromes

PheWeb

Q17_CRANIOSYNOSTOSIS

No definition available.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector
diagram bullet

Check conditions

not Q17_SYNDROMATA_MALFORMATIONUM_CONGENITAR_PRAECI_FACIEM_AFFIC1

392345

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 Q75.0
Hospital discharge: ICD-9 7560A
Hospital discharge: ICD-8 756
Cause of death: ICD-10 Q75.0
Cause of death: ICD-9 7560A
Cause of death: ICD-8 756

2 out of 7 registries used, show all original rules.

734

diagram downward connector

Check minimum number of events None

734

diagram downward connector

Include endpoints None

734

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

714

diagram downward connector
Q17_CRANIOSYNOSTOSIS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 714 338 376
Unadjusted prevalence (%) 0.19 0.16 0.23
Mean age at first event (years) 25.20 23.33 26.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.21 [0.70, 2.10] 5.0e-1 104
15 years 0.01 0.82 [0.50, 1.36] 4.5e-1 38
5 years 0.00 1.47 [0.86, 2.53] 1.6e-1 17
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: Q17_CRANIOSYNOSTOSIS – Craniosynostosis EXCLUDE syndromes
GWS hits:

Survival analyses between endpoints

↥

Plot

before Craniosynostosis EXCLUDE syndromes
after Craniosynostosis EXCLUDE syndromes

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Craniosynostosis EXCLUDE syndromes

↥

Endpoint not on priority list, no data to show.