Respiratory distress of newborn

P16_RESPI_DISTR_NEWBO

newborn respiratory distress syndrome: Infant acute respiratory distress syndrome is a lung disorder that affects premature infants caused by developmental insufficiency of surfactant production and structural immaturity of the lungs. The symptoms usually appear shortly after birth and may include tachypnea, tachycardia, chest wall retractions (recession), expiratory grunting, nasal flaring and cyanosis during breathing efforts.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 P22
Cause of death: ICD-10 P22

2 out of 7 registries used, show all original rules.

359

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Check minimum number of events None

359

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Include endpoints None

359

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Remove individuals based on genotype QC

332

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P16_RESPI_DISTR_NEWBO

Control definitions

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF4
Parent code in ICD-10 P2
Name in latin Dyspnoea neonatalis

Summary Statistics

Key figures

All Female Male
Number of individuals 332 160 172
Unadjusted prevalence (%) 0.09 0.08 0.10
Mean age at first event (years) 0.40 0.81 0.01

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: P16_RESPI_DISTR_NEWBO – Respiratory distress of newborn
GWS hits: 1

Survival analyses between endpoints

Plot

before Respiratory distress of newborn
after Respiratory distress of newborn

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Drugs most likely to be purchased after Respiratory distress of newborn

Endpoint not on priority list, no data to show.