Premature rupture of membranes

DOID MESH PheWeb

O15_MEMBR_PREMAT_RUPT

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O42

Hospital discharge: ICD-9 6581A

Hospital discharge: ICD-8 63495

Cause of death: ICD-10 O42

Cause of death: ICD-9 6581A

Cause of death: ICD-8 63495

2 out of 7 registries used, show all original rules.

7451

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Check minimum number of events None

7451

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Include endpoints None

7451

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Remove individuals based on genotype QC

7147

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O15_MEMBR_PREMAT_RUPT

Control definitions

Control exclude O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF5

Parent code in ICD-10 O30-O48

Name in latin Ruptura membranarum fetalium praematura

NAME	O15_MEMBR_PREMAT_RUPT
CONTROL_EXCLUDE	O15_MATERN_CARE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	O42
HD_ICD_9	6581A
HD_ICD_8	63495
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	O42
COD_ICD_9	6581A
COD_ICD_8	63495
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Premature rupture of membranes based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7147	7147	-
Unadjusted prevalence (%)	1.90	3.39	-
Mean age at first event (years)	30.52	30.52	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.79 [0.37, 1.66]	5.3e-1	38
15 years	0.00	0.56 [0.24, 1.31]	1.8e-1	12
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: O15_MEMBR_PREMAT_RUPT – Premature rupture of membranes
GWS hits: 1

Survival analyses between endpoints

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Plot

before Premature rupture of membranes
after Premature rupture of membranes

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Table

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Drugs most likely to be purchased after Premature rupture of membranes

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Endpoint not on priority list, no data to show.