Spontaneous abortion


habitual abortion: Three or more consecutive spontaneous abortions.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O03
Hospital discharge: ICD-9 634
Hospital discharge: ICD-8 643
Cause of death: ICD-10 O03
Cause of death: ICD-9 634
Cause of death: ICD-8 643

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude O15_PREG_ABORT

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O00-O08
Name in latin Abortus spontaneus

Summary Statistics

Key figures

All Female Male
Number of individuals 16906 16906 -
Unadjusted prevalence (%) 4.48 8.02 -
Mean age at first event (years) 30.44 30.44 -


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.57 [0.44, 0.72] 5.9e-6 316
15 years 0.00 0.38 [0.29, 0.51] 1.4e-10 95
5 years 0.00 0.23 [0.12, 0.43] 4.7e-6 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: O15_ABORT_SPONTAN – Spontaneous abortion
GWS hits:

Survival analyses between endpoints


before Spontaneous abortion
after Spontaneous abortion

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Drugs most likely to be purchased after Spontaneous abortion

Endpoint not on priority list, no data to show.