Other diseases of urinary system

DOID EFO MESH SNOMED PheWeb

N14_URINOTH

urinary system disease: A disease involving the renal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N30-N39

Cause of death: ICD-10 N30-N39

2 out of 7 registries used, show all original rules.

48844

Check minimum number of events None

48844

Include endpoints

N14_CYSTITIS

N14_NEUROMUSCDYSBLADD

N14_OTHBLADD

N14_BLADDDISINOTH

N14_URETHRITISANDURSYNDR

N14_URETHRALSTRICT

N14_URETHRAOTH

N14_URETHINOTH

51191

Remove individuals based on genotype QC

49276

N14_URINOTH

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	N14_URINOTH
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	N14_CYSTITIS\|N14_NEUROMUSCDYSBLADD\|N14_OTHBLADD\|N14_BLADDDISINOTH\|N14_URETHRITISANDURSYNDR\|N14_URETHRALSTRICT\|N14_URETHRAOTH\|N14_URETHINOTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N3
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	N3
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Other diseases of urinary system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	49276	35597	13679
Unadjusted prevalence (%)	13.07	16.89	8.23
Mean age at first event (years)	56.53	52.96	65.82

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.38 [3.05, 3.75]	<1e-100	7178
15 years	0.01	1.51 [1.37, 1.66]	4.5e-17	2186
5 years	0.01	4.32 [4.00, 4.68]	<1e-100	2695
1 year	0.00	11.54 [10.42, 12.79]	<1e-100	1772

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_URINOTH – Other diseases of urinary system
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other diseases of urinary system
after Other diseases of urinary system

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Other diseases of urinary system

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

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R6

R5

R4

R3