Other specified disorders of kidney and ureter

N14_OTHETNASKIDUR

renal artery obstruction: Narrowing or occlusion of the renal artery or arteries. It is due usually to atherosclerosis; fibromuscular dysplasia; thrombosis; embolism, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (hypertension, renovascular).

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N28.0, N28.8, N28.9
Hospital discharge: ICD-9 593[0-1]|5938
Hospital discharge: ICD-8 59322
Hospital discharge: excluded ICD-8 5938B
Cause of death: ICD-10 N28.0, N28.8, N28.9
Cause of death: ICD-9 593[0-1]|5938
Cause of death: ICD-8 59322
Cause of death: excluded ICD-8 5938B

2 out of 7 registries used, show all original rules.

902

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Check minimum number of events None

902

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Include endpoints None

902

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Remove individuals based on genotype QC

875

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N14_OTHETNASKIDUR

Control definitions

Control exclude N14_KIDUROTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 875 470 405
Unadjusted prevalence (%) 0.23 0.22 0.24
Mean age at first event (years) 50.48 46.50 55.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 7.48 [5.04, 11.11] 2.1e-23 122
15 years 0.02 3.27 [2.32, 4.61] 1.5e-11 44
5 years 0.01 6.77 [4.83, 9.49] 1.2e-28 42
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_OTHETNASKIDUR – Other specified disorders of kidney and ureter
GWS hits:

Survival analyses between endpoints

Plot

before Other specified disorders of kidney and ureter
after Other specified disorders of kidney and ureter

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other specified disorders of kidney and ureter

Endpoint not on priority list, no data to show.