HSIL lesion of the cervix uteri, vagina or vulva

N14_FEMALE_GENITAL_HSIL

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 D06, D07.1&, D07.2&, N87.1, N87.2, N89.1, N89.2, N90.1, N90.2
Hospital discharge: ICD-9 6221B|6221C|2331A|2333A|6230B|6230C|2333B
Cause of death: ICD-10 D06, D07.1&, D07.2&, N87.1, N87.2, N89.1, N89.2, N90.1, N90.2
Cause of death: ICD-9 6221B|6221C|2331A|2333A|6230B|6230C|2333B

2 out of 7 registries used, show all original rules.

6255

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Check minimum number of events None

6255

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Include endpoints None

6255

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Remove individuals based on genotype QC

5996

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N14_FEMALE_GENITAL_HSIL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

Similar endpoints

List of similar endpoints to HSIL lesion of the cervix uteri, vagina or vulva based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 5996 5996 -
Unadjusted prevalence (%) 1.59 2.84 -
Mean age at first event (years) 38.47 38.47 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.61 [1.72, 3.95] 6.0e-6 115
15 years 0.01 1.86 [1.23, 2.82] 3.3e-3 49
5 years 0.00 3.24 [1.96, 5.37] 4.9e-6 26
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_FEMALE_GENITAL_HSIL – HSIL lesion of the cervix uteri, vagina or vulva
GWS hits: 1

Survival analyses between endpoints

Plot

before HSIL lesion of the cervix uteri, vagina or vulva
after HSIL lesion of the cervix uteri, vagina or vulva

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Drugs most likely to be purchased after HSIL lesion of the cervix uteri, vagina or vulva

Endpoint not on priority list, no data to show.