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Female infertility

DOID EFO MESH SNOMED PheWeb

N14_FEMALEINFERT

male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N97
Cause of death: ICD-10 N97

2 out of 7 registries used, show all original rules.

9972

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Check minimum number of events None

9972

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Include endpoints

13844

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Remove individuals based on genotype QC

13142

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N14_FEMALEINFERT

Control definitions

Control exclude N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N80-N98
Name in latin Infertilitas feminae

Similar endpoints

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List of similar endpoints to Female infertility based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 13142 13142 -
Unadjusted prevalence (%) 3.49 6.23 -
Mean age at first event (years) 31.32 31.32 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.73 [0.55, 0.96] 2.4e-2 148
15 years 0.00 0.35 [0.24, 0.53] 4.7e-7 33
5 years 0.00 0.60 [0.32, 1.13] 1.1e-1 11
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_FEMALEINFERT – Female infertility
GWS hits: 4

Survival analyses between endpoints

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Plot

before Female infertility
after Female infertility

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Drugs most likely to be purchased after Female infertility

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Endpoint not on priority list, no data to show.