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Inflammatory diseases of female pelvic organs

DOID EFO MESH SNOMED PheWeb

N14_FEMALEGENINF

Pelvic Inflammatory Disease: Pelvic inflammatory disease (PID) is an acute or chronic inflammation in the pelvic cavity. It is most commonly caused by sexually transmitted diseases, including chlamydia and gonorrhea that have ascended into the uterus, fallopian tubes, or ovaries as a result of intercourse or childbirth, or of surgical procedures, including insertion of IUDs or abortion. PID may be either symptomatic or asymptomatic. It may cause infertility and it may raise the risk of ectopic pregnancy. PID is a disease associated with HIV infection.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N70-N77
Cause of death: ICD-10 N70-N77

2 out of 7 registries used, show all original rules.

15521

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Check minimum number of events None

15521

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Include endpoints

23505

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Remove individuals based on genotype QC

22575

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N14_FEMALEGENINF

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Inflammatory diseases of female pelvic organs based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

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Key figures

All Female Male
Number of individuals 22575 22575 -
Unadjusted prevalence (%) 5.99 10.71 -
Mean age at first event (years) 36.38 36.38 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.75 [0.61, 0.92] 5.1e-3 755
15 years 0.00 0.49 [0.39, 0.60] 8.0e-12 250
5 years 0.00 0.68 [0.52, 0.89] 5.4e-3 78
1 year 0.00 1.50 [1.01, 2.23] 4.4e-2 30

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_FEMALEGENINF – Inflammatory diseases of female pelvic organs
GWS hits:

Survival analyses between endpoints

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Plot

before Inflammatory diseases of female pelvic organs
after Inflammatory diseases of female pelvic organs

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Drugs most likely to be purchased after Inflammatory diseases of female pelvic organs

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Endpoint not on priority list, no data to show.