Endometriosis

N14_ENDOMETRIOSIS

endometriosis: The growth of functional endometrial tissue in anatomic sites outside the uterine body. It most often occurs in the pelvic organs.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N80
Hospital discharge: ICD-9 617
Hospital discharge: ICD-8 6253
Cause of death: ICD-10 N80
Cause of death: ICD-9 617
Cause of death: ICD-8 6253

2 out of 7 registries used, show all original rules.

15607

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Check minimum number of events None

15607

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Remove individuals based on genotype QC

15088

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N14_ENDOMETRIOSIS

Control definitions

Control exclude N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N80-N98
Name in latin Endometriosis

Similar endpoints

Summary Statistics

Key figures

All Female Male
Number of individuals 15088 15088 -
Unadjusted prevalence (%) 4.00 7.16 -
Mean age at first event (years) 37.48 37.48 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.42 [0.33, 0.53] 2.1e-13 482
15 years 0.00 0.29 [0.22, 0.37] 4.0e-22 151
5 years 0.00 0.23 [0.14, 0.36] 1.1e-10 23
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_ENDOMETRIOSIS – Endometriosis
GWS hits: 30

Survival analyses between endpoints

Plot

before Endometriosis
after Endometriosis

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