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Calculus of kidney and ureter

DOID EFO MESH SNOMED PheWeb

N14_CALCUKIDUR

nephrolithiasis: The presence of a calculus in the pelvis of the kidney; this is most often composed of mineral salts and proteins.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N20
Hospital discharge: ICD-9 592
Hospital discharge: ICD-8 592
Cause of death: ICD-10 N20
Cause of death: ICD-9 592
Cause of death: ICD-8 592

2 out of 7 registries used, show all original rules.

10247

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Check minimum number of events None

10247

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Include endpoints None

10247

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Remove individuals based on genotype QC

9713

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N14_CALCUKIDUR

Control definitions

Control exclude N14_UROLITHIASIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N20-N23
Name in latin Nephrolithiasis et/sive ureterolithiasis

Summary Statistics

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Key figures

All Female Male
Number of individuals 9713 3340 6373
Unadjusted prevalence (%) 2.58 1.58 3.83
Mean age at first event (years) 50.82 46.48 53.09

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.05 [0.83, 1.33] 6.9e-1 1267
15 years 0.00 0.77 [0.63, 0.94] 8.6e-3 561
5 years 0.00 1.21 [1.00, 1.46] 5.0e-2 227
1 year 0.00 2.23 [1.70, 2.92] 5.8e-9 74

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_CALCUKIDUR – Calculus of kidney and ureter
GWS hits: 18

Survival analyses between endpoints

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Plot

before Calculus of kidney and ureter
after Calculus of kidney and ureter

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Calculus of kidney and ureter

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Endpoint not on priority list, no data to show.