Disorders of breast

N14_BREAST

breast disease: A disease involving the breast.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector
diagram bullet

Apply sex-specific rule

Sex only females

219462

diagram downward connector

Check conditions None

219462

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N60-N64
Cause of death: ICD-10 N60-N64

2 out of 7 registries used, show all original rules.

14667

diagram downward connector

Check minimum number of events None

14667

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

16897

diagram downward connector
N14_BREAST

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 16897 16897 -
Unadjusted prevalence (%) 4.48 8.02 -
Mean age at first event (years) 46.31 46.31 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.70 [0.55, 0.89] 3.2e-3 712
15 years 0.00 0.55 [0.44, 0.69] 2.3e-7 307
5 years 0.00 0.85 [0.67, 1.10] 2.2e-1 112
1 year 0.00 0.73 [0.44, 1.22] 2.3e-1 17

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: N14_BREAST – Disorders of breast
GWS hits: 13

Survival analyses between endpoints

Plot

before Disorders of breast
after Disorders of breast

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of breast

Endpoint not on priority list, no data to show.