Acute nephritic syndrome

DOID EFO MESH SNOMED PheWeb

N14_ACUTENEPHRITIC

nephritis: Inflammation of renal tissue. [ NCIT:P378 ]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 N00#

Hospital discharge: ICD-9 580

Hospital discharge: ICD-8 580

Hospital discharge: excluded ICD-9 5804

Cause of death: ICD-10 N00#

Cause of death: ICD-9 580

Cause of death: ICD-8 580

Cause of death: excluded ICD-9 5804

2 out of 7 registries used, show all original rules.

607

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Check minimum number of events None

607

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Include endpoints None

607

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Remove individuals based on genotype QC

581

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N14_ACUTENEPHRITIC

Control definitions

Control exclude N14_GLOMERULAR

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 N00-N08

Name in latin Syndroma nephriticum acutum

NAME	N14_ACUTENEPHRITIC
CONTROL_EXCLUDE	N14_GLOMERULAR
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	N00
HD_ICD_9	580
HD_ICD_8	580
HD_ICD_10_EXCL
HD_ICD_9_EXCL	5804
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	N00
COD_ICD_9	580
COD_ICD_8	580
COD_ICD_10_EXCL
COD_ICD_9_EXCL	5804
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Acute nephritic syndrome based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	581	235	346
Unadjusted prevalence (%)	0.15	0.11	0.21
Mean age at first event (years)	36.13	33.85	37.68

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	1.67 [0.94, 2.98]	8.2e-2	86
15 years	0.01	1.10 [0.65, 1.88]	7.2e-1	31
5 years	0.00	2.91 [1.75, 4.84]	4.1e-5	21
1 year	0.00	7.88 [3.98, 15.61]	3.2e-9	11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: N14_ACUTENEPHRITIC – Acute nephritic syndrome
GWS hits:

Survival analyses between endpoints

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Plot

before Acute nephritic syndrome
after Acute nephritic syndrome

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Table

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Drugs most likely to be purchased after Acute nephritic syndrome

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Endpoint not on priority list, no data to show.