≡ Risteys
R9

Documentation Changelog GitHub Contact & Feedback

Paget disease

DOID EFO MESH SNOMED PheWeb

M13_PAGET

osteitis deformans: A disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue.

Endpoint definition

↥
FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M88
Hospital discharge: ICD-9 7310
Hospital discharge: ICD-8 72199
Cause of death: ICD-10 M88
Cause of death: ICD-9 7310
Cause of death: ICD-8 72199

2 out of 7 registries used, show all original rules.

119

diagram downward connector

Check minimum number of events None

119

diagram downward connector

Include endpoints None

119

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

115

diagram downward connector
M13_PAGET

Control definitions

Control exclude M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M86-M90
Name in latin Osteitis deformans Paget

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 115 50 65
Unadjusted prevalence (%) 0.03 0.02 0.04
Mean age at first event (years) 63.58 61.57 65.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: M13_PAGET – Paget disease
GWS hits:

Survival analyses between endpoints

↥

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Paget disease

↥

Endpoint not on priority list, no data to show.