Osteomyelitis

DOID EFO MESH SNOMED PheWeb

M13_OSTEOMYELITIS

osteomyelitis: An acute or chronic inflammation of the bone and its structures due to infection with pyogenic bacteria.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M86

Hospital discharge: ICD-9 730[0-9]

Hospital discharge: ICD-8 720

Cause of death: ICD-10 M86

Cause of death: ICD-9 730[0-9]

Cause of death: ICD-8 720

2 out of 7 registries used, show all original rules.

1817

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Check minimum number of events None

1817

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Include endpoints None

1817

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Remove individuals based on genotype QC

1758

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M13_OSTEOMYELITIS

Control definitions

Control exclude M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 M86-M90

Name in latin Osteomyelitis

NAME	M13_OSTEOMYELITIS
CONTROL_EXCLUDE	M13_OSTEOCHONDRO
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M86
HD_ICD_9	730[0-9]
HD_ICD_8	720
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M86
COD_ICD_9	730[0-9]
COD_ICD_8	720
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Osteomyelitis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1758	605	1153
Unadjusted prevalence (%)	0.47	0.29	0.69
Mean age at first event (years)	53.84	48.63	56.57

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	5.03 [3.43, 7.38]	1.4e-16	398
15 years	0.01	2.21 [1.60, 3.05]	1.6e-6	134
5 years	0.01	5.36 [4.09, 7.02]	3.7e-34	141
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_OSTEOMYELITIS – Osteomyelitis
GWS hits:

Survival analyses between endpoints

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Plot

before Osteomyelitis
after Osteomyelitis

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Table

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Drugs most likely to be purchased after Osteomyelitis

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Endpoint not on priority list, no data to show.