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Other disorders of the musculoskeletal system and connective tissue

DOID EFO MESH SNOMED PheWeb

M13_MUSCULOSKELEOTH

musculoskeletal system disease: A disease involving the musculoskeletal system. [database_cross_reference: MONDO:DesignPattern]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M95-M99
Cause of death: ICD-10 M95-M99

2 out of 7 registries used, show all original rules.

2934

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Check minimum number of events None

2934

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Include endpoints

4137

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Remove individuals based on genotype QC

3974

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M13_MUSCULOSKELEOTH

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other disorders of the musculoskeletal system and connective tissue based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 3974 2205 1769
Unadjusted prevalence (%) 1.05 1.05 1.06
Mean age at first event (years) 50.69 49.58 52.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.61 [1.13, 2.31] 9.2e-3 374
15 years 0.01 1.08 [0.81, 1.46] 5.9e-1 150
5 years 0.00 2.14 [1.61, 2.86] 1.8e-7 85
1 year 0.00 3.65 [2.39, 5.58] 2.2e-9 27

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_MUSCULOSKELEOTH – Other disorders of the musculoskeletal system and connective tissue
GWS hits:

Survival analyses between endpoints

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Plot

before Other disorders of the musculoskeletal system and connective tissue
after Other disorders of the musculoskeletal system and connective tissue

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other disorders of the musculoskeletal system and connective tissue

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Endpoint not on priority list, no data to show.