Early lumbar disc prolapse, operated

M13_EARLY_LUMBAR_PROLAPSE

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Pre-conditions 16<=EVENT_AGE<=44

Hospital Discharge: ICD-10 M51.1

Cause of death: ICD-10 M51.1

Operations: NOMESCO codes ^ABC16

3 out of 7 registries used, show all original rules.

8648

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Check minimum number of events None

8648

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Include endpoints None

8648

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Remove individuals based on genotype QC

8351

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M13_EARLY_LUMBAR_PROLAPSE

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF6

NAME	M13_EARLY_LUMBAR_PROLAPSE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS	16<=EVENT_AGE<=44
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M511
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M511
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM	^ABC16
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Early lumbar disc prolapse, operated based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	8351	4989	3362
Unadjusted prevalence (%)	2.21	2.37	2.02
Mean age at first event (years)	35.33	34.98	35.86

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.13 [1.54, 2.95]	4.7e-6	101
15 years	0.01	1.50 [1.00, 2.24]	5.1e-2	35
5 years	0.00	2.88 [1.59, 5.20]	4.5e-4	13
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_EARLY_LUMBAR_PROLAPSE – Early lumbar disc prolapse, operated
GWS hits: 3

Survival analyses between endpoints

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Plot

before Early lumbar disc prolapse, operated
after Early lumbar disc prolapse, operated

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Table

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Drugs most likely to be purchased after Early lumbar disc prolapse, operated

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Endpoint not on priority list, no data to show.