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Disorders of continuity of bone

MESH PheWeb

M13_BONECONTINUITY

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 M84
Cause of death: ICD-10 M84

2 out of 7 registries used, show all original rules.

2615

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Check minimum number of events None

2615

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Include endpoints None

2615

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Remove individuals based on genotype QC

2543

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M13_BONECONTINUITY

Control definitions

Control exclude M13_OSTEOCHONDRO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M80-M85
Name in latin Perturbationes continuitatis ossis

Summary Statistics

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Key figures

All Female Male
Number of individuals 2543 1623 920
Unadjusted prevalence (%) 0.67 0.77 0.55
Mean age at first event (years) 51.81 52.40 50.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.82 [1.67, 4.77] 1.1e-4 182
15 years 0.01 1.28 [0.70, 2.32] 4.2e-1 65
5 years 0.00 3.16 [1.91, 5.22] 7.3e-6 49
1 year 0.00 14.69 [9.06, 23.82] 1.3e-27 49

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: M13_BONECONTINUITY – Disorders of continuity of bone
GWS hits:

Survival analyses between endpoints

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Plot

before Disorders of continuity of bone
after Disorders of continuity of bone

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Disorders of continuity of bone

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Endpoint not on priority list, no data to show.