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Other and unspecified vasculitis limited to skin

DOID EFO MESH SNOMED PheWeb

L12_VASCULITISNAS

hypersensitivity vasculitis: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L95.8, L95.9
Cause of death: ICD-10 L95.8, L95.9

2 out of 7 registries used, show all original rules.

618

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Check minimum number of events None

618

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Include endpoints None

618

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Remove individuals based on genotype QC

600

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L12_VASCULITISNAS

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 600 337 263
Unadjusted prevalence (%) 0.16 0.16 0.16
Mean age at first event (years) 59.10 58.56 59.78

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.83 [2.02, 11.52] 3.9e-4 93
15 years 0.01 1.78 [0.69, 4.64] 2.4e-1 31
5 years 0.01 5.50 [2.50, 12.11] 2.3e-5 34
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_VASCULITISNAS – Other and unspecified vasculitis limited to skin
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unspecified vasculitis limited to skin
after Other and unspecified vasculitis limited to skin

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified vasculitis limited to skin

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Endpoint not on priority list, no data to show.